Pubblicazioni

Autori:

Spinelli, Antonello E.; Boschi, Federico

Titolo:

Photodynamic therapy using Cerenkov and radioluminescence light

Anno:

2021

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

Sì

Nome rivista:

FRONTIERS IN PHYSICS

ISSN Rivista:

2296-424X

N° Volume:

9

Numero o Fascicolo:

637120

Intervallo pagine:

1-7

Parole chiave:

photodynamic therapy; Cerenkov radiation; radioluminescence; nano particles; photosensitizer

Breve descrizione dei contenuti:

In this short review the potential use of Cerenkov radiation and radioluminescence as internal sources for Photodynamic therapy (PDT) is discussed. PDT has been developed over the course of more than 100 years and is based on the induced photo conversion of a drug called photosensitizer (PS) that triggers the production of cytotoxic reactive oxygen species (ROS) leading to the killing of the cells. In order to overcome the problem of light penetration in the tissues, different solutions were proposed in the past. The use of radioisotopes like: F-18, Cu-64, Y-90, Lu-177 as internal light sources increase the light fluence at the PS compared to an external source, resulting in a larger cytotoxic effect.

Pagina Web:

https://doi.org/10.3389/fphy.2021.637120

Id prodotto:

124972

Handle IRIS:

11562/1057938

ultima modifica:

18 novembre 2022

Citazione bibliografica:

Spinelli, Antonello E.; Boschi, Federico, Photodynamic therapy using Cerenkov and radioluminescence light «FRONTIERS IN PHYSICS» , vol. 9 , n. 637120 , 2021 , pp. 1-7

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