Speaker:
M. Dr. Massimiliano Tuveri
- Azienda Ospedaliera Universitaria Integrata - Verona
Wednesday, January 22, 2020
at
11:30 AM
Aula M
In the cardiovascular system, morphology and functionality are closely related. Altered flow conditions, such as separa- tion and flow-reversal zones, low and oscillatory shear-stress zones, play an important role in the development of arterial disease. In turn, all these flow conditions are modified by arte- rial wall changes such as intimal thickening or atherosclerotic plaques. A detailed understanding of the local hemodynamic environment, the influence of wall modifications on flow pat- terns and the long-term adaptions of the vascular wall after surgical procedures can have useful clinical applications, es- pecially in view of reconstruction and revascularization op- erations. Some of these alterations are not well understood, making it quite difficult to foresee short- and long-term evo- lution of the atherosclerotic disease and to plan an aggressive approach. Recent advances in data-acquisition technology are now providing physicians with large amounts of quantita- tive information on vascular geometry that, together with the availability of sophisticated three-dimensional simulation methods, can be used to build patient-parametrized models able to give detailed predictions on, e.g., flow shears stresses and zones of recirculation in the arterial wall regions.