Proton therapy kills cancer cells by delivering proton beams to the tumour. Opposite to conventional radiation therapy, proton beams deposit their maximum energy within a precisely defined range, known as the Bragg peak. This is due to the stopping power of the atoms in the body of the patient.
To proceed the treatment, a plan is draw on a 3D image (a CT scan) of the patient. The Gross Tumour Volum is segmented and the Organs At Risk (OAR) are also identified to be protected during the treatment. The plan allows to maximize the dosis on the tumour and minimize the dosis on the OAR. The patient is treated in the room on the basis of the 3D scan taken before the treatment.
Our research has led to the development of an imaging system (a cone beam CT) which is in the treatment room and which allows to adapt the treatment by using different image processing tools, among which deformable coregistration and contours tracking are essential. This allow to implement adaptive protontherapy, including on mobile tumours and reduce the range uncertainties.
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