The laboratory offers the student to get a deep insight of the theoretical basis of the principal bioinformatic tools. In this laboratory, special attention is put on the biomolecular data abases.
Introduction to bioinformatics.
Biomolecular Data bases:
PubMed
Nucleotidic Data Bases: EML, GenBank
Protein Data Bases: PIR, SwissProt, TREMBL
Structural Data Bases: PDB, NDB.
Genomic Projects: ENSEMBL, TIGR
Gene Onthology
Search and Alignments Algoritms
FASTA and BLAST
PSI-BLAST and profile definition
Substitution matrices
Alignment algoritms: Needleman e Wunsch and Smith-Waterman
Multiple sequence alignment programs: CLUSTALW, T-Coffee
ROC curves
written
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